cleanUrl: "toast-usage"

Quickstart

design_out = makeDesign(design, prop)
fitted_model = fitModel(design_out, Y_raw)
fitted_model$all_coefs # List all phenotyep names
fitted_model$all_cell_types # List all cell type names

res_table = csTest(fitted_model, coef='age',
									cell_type='Neuron', contrast_matrix=NULL)

• 아래 정보를 알 때 cell-type specific DE 분석을 수행한다.

  • Cell type proportion
  • Expression

• 데이터 준비

  • Y_raw gene (probe) x sample matrix (꼭 matrix 혹은 SummarizedExperiment 여야 한다)
  • prop sample x cell_type matrix
  • design 실험 조건 저장된 dataframe